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p40p40 monoclonal antibodyDiagnosing non-small cell lung cancer by morphology in small samples(e.g. biopsy, cell block, FNA) can be difficult. In these cases, given that conserving tissue for molecular testing is a priority, an effective immunohistochemistry (IHC)-based diagnostic approach is warranted.
At present, p63 is the most frequently used marker for lung squamous cell carcinoma (SqCC). p63 is extremely sensitive for SqCC; however, it suffers from specificity limitations, due to its reactivity in a subset of lung adenocarcinomas. p40 is a relatively unknown antibody that recognizes ΔNp63, a p63 isoform suggested to be highly specific for squamous/basal cells1. p40 may be a valuable marker inimproving the specificity over p63.

Disclaimer: Biozatix Indonesia adalah distributor yang menyediakan alat-alat laboratorium, alat kesehatan, serta reagensia elisa kits, immunohistochemistry (IHC),  antibody, research grade chemical, western blot, HPLC colomn, alat patologi.

Highly specific and sensitive marker to aid in the differentiation of lung squamous cell carcinoma vs. lung adenocarcinoma